Amorolfine HCL ( —— )

产品货号. M22881 CAS No. 106614-68-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Amorolfine HCL
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Amorolfine HCL is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase.
产品描述

Amorolfine HCL is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase. These enzymes can deplete ergosterol and cause ignosterol to accumulate in the fungal cytoplasmic cell membranes.
同义词

——
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibiotic
研究领域

Immune system/Infection
适应症

Onychomycosis

CAS Number

106614-68-0
分子量

354
分子式

C21H36ClNO?
纯度

>98% (HPLC)
溶解度

DMSO:12.5 mg/mL (35.31 mM; Need ultrasonic);H2O:3.33 mg/mL (9.41 mM; Need ultrasonic)
SMILES

CCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C.Cl
化学全称

——

1. Espinel-Ingroff A, et al. Antimicrob Agents ChemOthers. 1984 Jul; 26(1):5-9.

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